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Comparison of Strategies A and B for Estimating the AD Locus From the APOE Data Set
| Data Set | Strategy | Positiona | 95% PI width | Size of cluster 1b |
|---|---|---|---|---|
| All 30 markers | A | 0.4366 | 0.0283 | 82 |
| B | 0.4272 | 0.0168 | 95 | |
| 29 markers without APOE-4 | A | 0.4269 | 0.0299 | 62 |
| B | 0.4247 | 0.0149 | 106 |
The true APOE-4 location is at 425 kb, corresponding to 0.425 cM.
The number of haplotypes assigned to cluster 1 (the mutation-taking cluster). The total number of disease haplotypes was 372.
