Table 4.

Depth of the Mapped PANTHER/X Terms in GO

	GO depth with equivalent PANTHER/X-GO mapping		GO depth with a more general GO category mapped to PANTHER/X
PANTHER/X level	Molecular function	Biological process	Molecular function	Biological process
Level 1	1.90 ± 0.78	2.78 ± 0.85	1.25 ± 0.50	2.5 ± 1.00
Level 2	3.61 ± 1.21	4.22 ± 1.30	2.18 ± 1.12	3.29 ± 1.04
Level 3	4.45 ± 1.11	5.04 ± 1.09	3.36 ± 1.12	3.52 ± 2.27
Overall	3.68 ± 1.36	4.27 ± 1.37	2.32 ± 1.20	3.32 ± 1.58

For each level of PANTHER/X, we calculated the average (standard deviation) depth, in the Gene Ontology, of the GO term to which a PANTHER/X term was mapped. We calculated statistics separately for PANTHER/X terms that could be mapped to an equivalent GO term, versus PANTHER/X terms that could only be mapped to a more general GO term.