Table 1.
Stability of 25 mg/mL methotrexate solution for injection packaged in polypropylene syringes.
Time (days) | % of initial concentration remaining (mean ± SD; CV%) (n = 3) | |
---|---|---|
25 mg/mL | 25 mg/mL | |
23°C dark | +2 to +8°C dark | |
1 | 101.2 ± 1.6; 1.6 | 101.2 ± 0.3; 0.3 |
7 | 101.2 ± 0.3; 0.3 | 100.3 ± 1.0; 1.0 |
14 | 100.0 ± 1.0; 1.0 | 99.0 ± 2.3; 2.3 |
28 | 100.0 ± 0.8; 0.8 | 99.2 ± 0.3; 0.3 |
56 | 100.3 ± 0.8; 0.8 | 99.0 ± 0.5; 0.5 |
84 | 102.2 ± 1.1; 1.0 | 102.5 ± 2.3; 2.2 |