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. 2014 May 12;2014:689308. doi: 10.1155/2014/689308

Table 1.

Stability of 25 mg/mL methotrexate solution for injection packaged in polypropylene syringes.

Time (days) % of initial concentration remaining (mean ± SD; CV%) (n = 3)
25 mg/mL 25 mg/mL
23°C dark +2 to +8°C dark
1 101.2 ± 1.6; 1.6 101.2 ± 0.3; 0.3
7 101.2 ± 0.3; 0.3 100.3 ± 1.0; 1.0
14 100.0 ± 1.0; 1.0 99.0 ± 2.3; 2.3
28 100.0 ± 0.8; 0.8 99.2 ± 0.3; 0.3
56 100.3 ± 0.8; 0.8 99.0 ± 0.5; 0.5
84 102.2 ± 1.1; 1.0 102.5 ± 2.3; 2.2