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. Author manuscript; available in PMC: 2014 May 28.
Published in final edited form as: Genet Med. 2010 Apr;12(4):212–218. doi: 10.1097/GIM.0b013e3181d56ae6

Table 1. Relationship of perceived risk, worry, and perceived control to familial risk computed on the basis of detailed family history.

Adjusted means and 95% confidence intervalsa

Family history risk category N (%)b Perceived risk Worry Perceived control
Coronary heart disease
 Weak 947 (41) 2.42 (2.37–2.48) 1.68 (1.62–1.73) 4.32 (4.28–4.36)
 Moderate 615 (27) 2.75 (2.69–2.82) 1.90 (1.82–1.96) 4.33 (4.28–4.39)
 Strong 768 (33) 3.01 (2.95–3.07) 2.04 (1.97–2.10) 4.37 (4.32–4.42)
 Total 2330
F 97.0 37.7 1.12
P <0.001 <0.001 0.326
 Effect size (SD) 0.69 0.43 0.07
Stroke
 Weak 1212 (53) 2.52 (2.48–2.57) 1.44 (1.40–1.49) 4.01 (3.96–4.05)
 Moderate 783 (34) 2.74 (2.69–2.80) 1.61 (1.56–1.66) 4.02 (3.96–4.07)
 Strong 335 (14) 2.91 (2.83–3.00) 1.71 (1.63–1.79) 4.07 (3.98–4.16)
 Total 2330
F 36.16 20.11 0.82
P <0.001 <0.001 0.443
 Effect size (SD) 0.43 0.33 0.08
Diabetes
 Weak 1426 (61) 2.41 (2.36–2.46) 1.43 (1.39–1.48) 4.08 (4.04–4.12)
 Moderate 643 (28) 3.00 (2.93–3.06) 1.75 (1.69–1.81) 4.15 (4.08–4.21)
 Strong 261 (11) 3.30 (3.20–3.41) 1.96 (1.86–2.06) 4.13 (4.04–4.23)
 Total 2330
F 176.51 63.62 1.62
P <0.001 <0.001 0.198
 Effect size (SD) 0.86 0.59 0.06
Colon cancer
 Weak 2015 (88) 2.60 (2.57–2.64) 1.36 (1.33–1.39) 3.80 (3.76–3.83)
 Moderate 263 (11) 3.26 (3.16–3.35) 1.68 (1.59–1.76) 3.85 (3.75–3.95)
 Strong 52 (2) 3.53 (3.32–3.74) 1.90 (1.71–2.09) 3.89 (3.66–4.11)
 Total 2330
F 116.33 36.49 0.73
P <0.001 <0.001 0.484
 Effect size (SD) 1.12 0.75 0.11
Breast cancer (women only)
 Weak 1251 (76) 2.72 (2.68–2.76) 1.83 (1.78–1.88) 3.32 (3.27–3.38)
 Moderate 233 (14) 3.45 (3.36–3.54) 2.17 (2.05–2.29) 3.27 (3.15–3.40)
 Strong 172 (10) 3.58 (3.47–3.69) 2.26 (2.12–2.39) 3.26 (3.12–3.40)
 Total 1656
F 179.10 26.19 0.52
P <0.001 <0.001 0.597
 Effect size (SD) 1.05 0.46 0.06
Ovarian cancer (women only)
 Weak 1383 (9) 2.75 (2.72–2.79) 1.42 (1.38–1.46) 2.97 (2.92–3.02)
 Moderate 84 (6) 3.17 (3.03–3.31) 1.65 (1.49–1.81) 2.97 (2.78–3.17)
 Strong 56 (4) 2.99 (2.81–3.16) 1.56 (1.36–1.76) 3.03 (2.80–3.27)
 Total 1523c
F 19.05 4.55 0.13
P <0.001 0.011 0.875
 Effect size (SD) 0.35 0.18 0.07
a

The means listed above are all adjusted for the following covariates: gender, age, global health status, fruit and vegetable intake, minutes per week of physical activity, smoking (never, former, and current smoker), body mass index, education, and practice site. Unadjusted means (not shown) are similar to the adjusted means.

b

Percents may not add to 100% because of rounding.

c

Total N is lower for ovarian cancer, because women who had had both ovaries removed were not asked about perceived risk for ovarian cancer, worry, or control.