Table 6. Impact of platelet transfusion and patient factors on the mortality at day 7.
| Model 1 | Model 2 | Model 3 | Model 4 | Model 5 | ||||||||||||||||||||
| Effect of APA on survival | Effect of FFP and PLT on survival | Effect of FFP on survival | Effect of PLT on survival | Effect of broad APA on survival | ||||||||||||||||||||
| Univariate | Multivariate | Multivariate | Multivariate | Multivariate | Multivariate | |||||||||||||||||||
| Variables | B | OR | P | 95% CI | B | OR | P | 95% CI | B | OR | P | 95% CI | B | OR | P | 95% CI | B | OR | P | 95% CI | B | OR | P | 95% CI |
| Age | 0.01 | 1.01 | 0.19 | 0.99-1.03 | 0.03 | 1.03 | 0.1 | 1.00-1.06 | 0.02 | 1.02 | 0.22 | 0.99-1.05 | 0.02 | 1.02 | 0.2 | 0.98-1.05 | 0.03 | 1.03 | 0.1 | 1.00-1.06 | 0.03 | 1.03 | 0.04 | 1.00-1.06 |
| Sex | 0.03 | 1.01 | 0.67 | 0.72-1.69 | ||||||||||||||||||||
| Elapsed time | -0.01 | 0.98 | 0.29 | 0.96-1.01 | ||||||||||||||||||||
| Glasgow coma scale | -0.55 | 0.57 | <0.0001 | 0.50-0.64 | -0.44 | 0.64 | <0.0001 | 0.57-0.74 | -0.43 | 0.66 | <0.0001 | 0.57-0.75 | -0.43 | 0.65 | <0.0001 | 0.57-0.74 | -0.43 | 0.65 | <0.0001 | 0.57-0.74 | -0.44 | 0.65 | <0.0001 | 0.57-0.73 |
| Chronic Renal Failure | 0.47 | 1.61 | 0.14 | 0.85-3.02 | ||||||||||||||||||||
| Liver cirrhosis | 1.22 | 3.3 | 0.02 | 1.30-8.56 | 0.88 | 2.4 | 0.24 | 0.55-10.5 | 0.92 | 2.5 | 0.25 | 0.52-12.0 | 0.9 | 2.47 | 0.25 | 0.53-11.4 | 0.9 | 2.47 | 0.24 | 0.54-11.2 | 0.82 | 2.27 | 0.28 | 0.52-9.86 |
| Hypertension | -0.13 | 0.88 | 0.72 | 0.42-1.82 | -0.71 | 0.43 | 0.28 | 0.14-1.77 | -0.59 | 0.56 | 0.39 | 0.15-2.14 | -0.65 | 0.52 | 0.34 | 0.14-1.99 | -0.56 | 0.4 | 0.57 | 0.15-2.11 | -0.65 | 0.52 | 0.31 | 0.15-1.83 |
| CHD | 0.35 | 1.41 | 0.48 | 0.54-3.67 | ||||||||||||||||||||
| Diabetes mellitus | -0.58 | 0.56 | 0.12 | 0.27-1.15 | -0.56 | 0.57 | 0.30 | 0.20-1.66 | -0.6 | 0.55 | 0.29 | 0.18-1.66 | -0.6 | 0.55 | 0.29 | 0.18-1.67 | -0.63 | 0.53 | 0.18 | 0.12-1.57 | -0.48 | 0.62 | 0.37 | 0.22-1.76 |
| Atrial fibrillation | -1.05 | 0.34 | 0.33 | 0.04-2.95 | ||||||||||||||||||||
| TIA | 0.47 | 1.60 | 0.32 | 0.63-4.05 | ||||||||||||||||||||
| Anti-platelet agents | 0.17 | 1.18 | 0.61 | 0.62-2.24 | 1.63 | 5.12 | 0.006 | 1.59-16.5 | 1.91 | 6.78 | 0.004 | 1.84-24.9 | 1.78 | 5.91 | 0.006 | 1.68-20.9 | 1.86 | 6.48 | 0.003 | 1.88-22.3 | ||||
| Warfarin | 0.35 | 1.42 | 0.37 | 0.66-3.07 | -0.28 | 0.76 | 0.7 | 0.18-3.1 | 0.37 | 1.44 | 0.67 | 0.27-7.68 | 0.25 | 1.28 | 0.77 | 0.25-6.51 | 0.03 | 1.03 | 0.97 | 0.23-4.71 | -0.19 | 0.83 | 0.8 | 0.2-3.4 |
| Broad APA | 0.15 | 1.16 | 0.57 | 0.70-1.92 | 0.99 | 2.7 | 0.06 | 0.95-7.63 | ||||||||||||||||
| Location | ||||||||||||||||||||||||
| subcortical | -0.24 | 0.79 | 0.43 | 0.44-1.43 | ||||||||||||||||||||
| supratentorial | -0.33 | 0.72 | 0.14 | 0.47-1.11 | ||||||||||||||||||||
| infratentorial | 0.73 | 2.01 | 0.002 | 1.31-3.28 | 0.23 | 1.26 | 0.53 | 0.61-2.6 | 0.36 | 1.42 | 0.36 | 0.67-3.03 | 0.37 | 1.28 | 0.76 | 0.68-3.07 | 0.23 | 1.25 | 0.55 | 0.60-2.61 | 0.24 | 1.27 | 0.52 | 0.62-2.60 |
| Volume of ICH | 0.003 | 1.01 | <0.0001 | 1.006-1.01 | 0.003 | 1.003 | 0.06 | 1.00-1.01 | 0.004 | 1.004 | 0.04 | 1-1.01 | 0.004 | 1.002 | 0.04 | 1.00-1.01 | 0.003 | 1.003 | 0.046 | 1-1.007 | 0.003 | 1.003 | 0.06 | 1-1.006 |
| Disease progression | 3.96 | 52.5 | <0.0001 | 20.6-133.9 | 3.46 | 32 | <0.0001 | 10.24-99.7 | 3.5 | 33.1 | <0.0001 | 10.1-108.1 | 3.47 | 32.2 | <0.0001 | 10.1-102.6 | 3.51 | 33.4 | <0.0001 | 10.4-107.7 | 3.28 | 26.6 | <0.0001 | 9.18-77.2 |
| Operation | 0.63 | 1.89 | <0.0001 | 1.39-2.54 | ||||||||||||||||||||
| IVH | 0.20 | 1.23 | 0.40 | 0.76-1.97 | ||||||||||||||||||||
| Platelet count | -0.04 | 0.96 | 0.011 | 0.93-0.99 | -0.006 | 0.98 | 0.47 | 0.93-1.03 | -0.04 | 0.97 | 0.21 | 0.91-1.02 | -0.03 | 0.97 | 0.22 | 0.92-1.02 | -0.03 | 0.97 | 0.32 | 0.92-1.03 | -0.02 | 0.98 | 0.32 | 0.93-1.03 |
| PT | -0.02 | 0.99 | 0.001 | 0.98-0.99 | ||||||||||||||||||||
| aPTT | 0.04 | 1.02 | 0.11 | 0.99-1.05 | ||||||||||||||||||||
| Fibrinogen | -0.001 | 1.00 | 0.52 | 0.99-1.00 | 0.001 | 1 | 0.8 | 0.93-1.03 | 0.001 | 1 | 0.98 | 1.00-1.01 | 0.0001 | 1 | 0.98 | 0.997-1.003 | 0.0001 | 1 | 0.91 | 0.997-1.003 | 0.001 | 1.001 | 0.72 | 0.998-1.003 |
| Platelet transfusion | -0.98 | 4.02 | 0.07 | 0.90-18.1 | -1.49 | 0.23 | 0.26 | 0.02-3.02 | -2.62 | 0.03 | 0.07 | 0.01-0.75 | ||||||||||||
| FFP transfusion | 1.44 | 4.20 | 0.009 | 1.44-12.3 | 2.23 | 0.04 | 0.008 | 1.81-48.0 | 2.59 | 13.3 | 0.001 | 2.85-62.6 | ||||||||||||
CHD: coronary heart disease; PH of TIA: past history of transient ischemic attack; APA: anti-platelet agents; IVH: intraventricular hemorrhage.
ICH: intracerebral hemorrhage; PT: prothrombin time; aPTT: activated partial thromboplastin time; OR: odds ratio; CI: confidence interval.