Table 7. Impact of platelet transfusion and patient factors on the mortality at day 90.
| Model 1 | Model 2 | ||||||||||
| Effect of APA on survival | Effect of PLT on survival | ||||||||||
| Univariate | Multivariate | Multivariate | |||||||||
| Variables | B | HR | P | 95% CI | B | HR | P | 95% CI | B | HR | P |
| Age | 0.01 | 1.01 | 0.19 | 0.99–1.02 | 0.01 | 1.01 | 0.1 | 0.99–1.02 | 0.01 | 1.01 | 0.22 |
| Sex | 0.07 | 1.01 | 0.67 | 0.79–1.45 | |||||||
| Elapsed time | −0.02 | 0.98 | 0.10 | 0.96–1.004 | |||||||
| Glasgow coma scale | −0.38 | 0.68 | <0.0001 | 0.64–0.73 | −0.28 | 0.76 | <0.0001 | 0.69–0.82 | −0.27 | 0.77 | <0.0001 |
| Chronic Renal Failure | 0.28 | 1.33 | 0.21 | 0.85–2.08 | |||||||
| Liver cirrhosis | 0.85 | 2.33 | 0.002 | 1.37–3.95 | 0.51 | 1.7 | 0.13 | 0.86–3.22 | 0.59 | 1.8 | 0.25 |
| Hypertension | −0.09 | 0.91 | 0.71 | 0.57–1.49 | −0.26 | 0.77 | 0.35 | 0.45–1.33 | −0.21 | 0.81 | 0.39 |
| CHD | 0.35 | 1.41 | 0.51 | 0.48–3.67 | |||||||
| Diabetes mellitus | −0.15 | 0.86 | 0.52 | 0.55–1.36 | −0.15 | 0.86 | 0.58 | 0.51–1.47 | −0.17 | 0.84 | 0.29 |
| Atrial fibrillation | −1.05 | 0.34 | 0.33 | 0.04–1.95 | |||||||
| TIA | 0.47 | 1.60 | 0.32 | 0.63–3.04 | |||||||
| Anti-platelet agents | 0.21 | 1.24 | 0.28 | 0.84–1.82 | 0.62 | 1.87 | 0.006 | 1.20–2.91 | 0.64 | 1.9 | 0.004 |
| Warfarin | 0.26 | 1.30 | 0.37 | 0.74–2.28 | 0.1 | 0.76 | 0.76 | 0.59–2.04 | 0.21 | 1.24 | 0.67 |
| Location | |||||||||||
| subcortical | −0.13 | 0.88 | 0.54 | 0.59–1.32 | |||||||
| supratentorial | −0.26 | 0.77 | 0.08 | 0.57–1.04 | |||||||
| infratentorial | 0.48 | 1.61 | 0.002 | 1.19–2.18 | 0.08 | 1.08 | 0.69 | 0.74–1.56 | 0.06 | 1.07 | 0.36 |
| Volume of ICH | 0.004 | 1.004 | <0.0001 | 1.003–1.005 | 0.001 | 1.001 | 0.06 | 1.00–1.003 | 0.001 | 1.001 | 0.06 |
| Disease progression | 2.94 | 18.9 | <0.0001 | 9.98–35.95 | 2.43 | 11.3 | <0.0001 | 4.84–26.6 | 2.4 | 11.5 | <0.0001 |
| Operation | 0.63 | 1.89 | <0.0001 | 1.39–2.54 | |||||||
| IVH | 0.20 | 1.23 | 0.40 | 0.76–1.97 | |||||||
| Platelet count | −0.04 | 0.96 | 0.001 | 0.94–0.99 | 0.001 | 1.001 | 0.95 | 0.98–1.03 | −0.001 | 0.97 | 0.21 |
| PT | −0.009 | 0.99 | 0.002 | 0.98–0.99 | |||||||
| aPTT | 0.001 | 1.02 | 0.99 | 0.99–1.01 | |||||||
| Fibrinogen | −0.001 | 1.00 | 0.29 | 0.99–1.001 | 0.001 | 1 | 0.81 | 0.99–1.002 | 0.001 | 1 | 0.98 |
| Platelet transfusion | −0.97 | 0.38 | 0.09 | 0.12–1.18 | −1.74 | 0.18 | 0.09 | ||||
| FFP transfusion | 1.08 | 2.96 | 0.02 | 1.21−7.18 | |||||||
CHD: coronary heart disease; TIA: transient ischemic attack; APA: anti-platelet agents; IVH: intraventricular hemorrhage.
ICH: intracerebral hemorrhage; PT: prothrombin time; aPTT: activated partial thromboplastin time; HR:hazard ratio; CI: confidence interval.