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. 2014 May 28;9(5):e97272. doi: 10.1371/journal.pone.0097272

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© 2014 Graudenzi et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Time-variation of the Moran Index, MI (eq. 10) (A) and of the Pearson Coefficient, PC (eq. 11) (B). In (D) the Spatial Correlation (eq. 8) with the relative standard deviation (E) is displayed, for the four initial conditions. A crypt can be considered well stratified if its MI is high (it is indeed stratified), and its PC is high (it has the cellular populations in the correct order), according to a template (C).

Inline graphic — Time-variation of the Moran Index, MI (eq. 10) (A) and of the Pearson Coefficient, PC (eq. 11) (B). In (D) the Spatial Correlation (eq. 8) with the relative standard deviation (E) is displayed, for the four initial conditions. A crypt can be considered well stratified if its MI is high (it is indeed stratified), and its PC is high (it has the cellular populations in the correct order), according to a template (C).