Table 5. Murine colonization experiments.
LOG CFU retrieved after | ||||
Single strain administration | Simultaneous administration | |||
B. breve UCC2003 | B. breve UCC2003-luxS | B. breve UCC2003 | B. breve UCC2003-luxS | |
Small intestine | 6.39±0.09 | 1.76±1.15 * | 5.94±0.43 | BDL |
Cecum | 6.87±0.06 | 2.84±0.67 * | 6.96±0.43 | BDL |
Large intestine | 6.51±1.34 | 0.85±1.15 * | 6.52±0.43 | BDL |
LOG CFU of B. breve UCC2003 or B. breve UCC2003-luxS, retrieved from the murine small intestine, cecum and large intestine (15 days after the last administration). Data are shown for single strain administration as well as for the simultaneous administration of equal numbers of both strains. Numbers shown are means ± SEM. BDL: below detection limit. (*, significantly lower than WT; p<0.05, n = 7).