Figure 2.
(A) The time dependencies of the root-mean-square deviations (RMSDs) for the back bone atoms of the p300/H3/Ac-CoA complex, p300, H3 and Ac-CoA from their initial positions during the 100 ns simulation. (B) Residue fluctuations obtained by average residual fluctuations over 100 ns simulation and experimental result calculated from B factors of p300 (PDB code: 3BIY). The residue number of genetically deleted autoacetylation loop was represented by a gap. The color of the cartoon structure ranges from blue to red with increasing RMSF values.