Table 1.

Results of HOPS and RIO for the Test Set of Putative Orthologs for H. sapiens and D. melanogaster

H. sapiens	D. melanogaster	Domain	HOPS (%)	RIO (%)
143E_HUMAN	143E_DROME	14-3-3	100	98
ADHX_HUMAN	ADHX_DROME	adh_zinc	16.5	0
APE1_HUMAN	RRP1_DROME	Exo_endo_phos	100	85
ARF1_HUMAN	ARF1_DROME	arf	89.5	92
ARI1_HUMAN	ARI1_DROME	IBR	100	96
ARL1_HUMAN	ARL1_DROME	arf	100	100
ATPG_HUMAN	ATPG_DROME	ATP-synt	100	100
ATPO_HUMAN	ATPO_DROME	OSCP	100	63
CAPB_HUMAN	CAPB_DROME	F_actin_cap_B	100	95
CG1C_HUMAN	CG1C_DROME	Cyclin	100	80
CLAT_HUMAN	CLAT_DROME	Carn_acyltransf	94	89
COXA_HUMAN	COXA_DROME	COX5A	99	78
DYNA_HUMAN	DYNA_DROME	CAP_GLY	50.5	29
ERH_HUMAN	ER_DROME	ER	100	98
FAC2_HUMAN	FAC2_DROME	Abi	87	62
H2AZ_HUMAN	H2AV_DROME	Histone	76	21
H4_HUMAN	H4_DROME	Histone	62	1
IF2A_HUMAN	IF2A_DROME	S1	78	62
KC2B_HUMAN	KC2B_DROME	CK_II_beta	18.5	36
MCM2_HUMAN	MCM2_DROME	MCM	100	97
MCM4_HUMAN	MCM4_DROME	MCM	100	100
PP1B_HUMAN	PP1B_DROME	Metallophos	76	43
PRS8_HUMAN	PRS8_DROME	AAA	84.5	—
PSA2_HUMAN	PSA2_DROME	Proteasome	99.5	98
PSA3_HUMAN	PSA3_DROME	Proteasome	74.5	13
PSA4_HUMAN	PSA4_DROME	Proteasome	100	100
PSA5_HUMAN	PSA5_DROME	Proteasome	79	95
PSA6_HUMAN	PSA6_DROME	Proteasome	77	44
PSB1_HUMAN	PSB1_DROME	Proteasome	50.5	37
PSB3_HUMAN	PSB3_DROME	Proteasome	72.5	22
PURA_HUMAN	PURA_DROME	Adenylsucc_synt	100	100
RA51_HUMAN	RA51_DROME	HHH	0	0
RBJK_HUMAN	RBJK_DROME	TIG	97	48
RLA1_HUMAN	RLA1_DROME	60s_ribosomal	35	12
RLA2_HUMAN	RLA2_DROME	60s_ribosomal	45.5	21
RPB2_HUMAN	RPB2_DROME	RNA_pol_B	100	96
RPB6_HUMAN	RPB6_DROME	RNA_pol_Rpb6	90	62
RS18_HUMAN	RS18_DROME	Ribosomal_S13	24	3
RTC1_HUMAN	RTC1_DROME	RTC	100	6
SSB_HUMAN	SSB_DROME	SSB	97.5	92
T2DA_HUMAN	T2DA_DROME	TFIID_A	82.5	87
T2FB_HUMAN	T2FB_DROME	TFIIF_beta	100	98
TCPA_HUMAN	TCPA_DROME	cpn60_TCP1	99.5	60
TCPG_HUMAN	TCPG_DROME	cpn60_TCP1	97	57
UBCI_HUMAN	O62622	UQ_con	100	96
VATF_HUMAN	VAF1_DROME	ATP-synt_F	97	54
XPA_HUMAN	XPA_DROME	XPA	100	67

A “—” indicates no results reported.