Table 4.
Iron status and markers of inflammation in serum between cases with colonic iron presence (+) and without iron presence (-)
|
Iron (+) |
Iron (-) |
P-value* |
P-value† |
|
|---|---|---|---|---|
| (n = 6) | (n = 14) | |||
|
Hb (g/dL) |
12.8 (2.0) |
11.2 (3.4) |
0.20 |
- |
|
sTfR (nmol/L) |
11.0 (14.3) |
22.2 (18.0) |
0.11 |
0.32 |
|
Hepcidin (ng/mL) |
80.8 (28.6) |
22.0 (48.4) |
0.02 |
0.12 |
|
CRP (μg/mL) |
7.7 (3.4) |
7.9 (3.4) |
0.43 |
0.31 |
|
IL-6 (pg/mL) |
2.5 (3.0) |
2.7 (2.0) |
0.99 |
0.86 |
| TNF-α (pg/mL) | 0.27 (0.3) | 0.38 (0.3) | 0.46 | 0.41 |
Values shown as median (IQR).
*p-value of difference between iron(+) and iron (-) using non-parametric Mann–Whitney U test.
†p-value of difference between iron(+) and iron (-) adjusting for Hb with multiple linear regression.
Hb, hemoglobin; sTfR, serum transferrin receptor; CRP, c-reactive protein; IL-6, interleukin-6; TNF-α, tumor necrosis factor-alpha.