TABLE 3.
Vascular characteristics of the study population across time points.
| Characteristic | EMI and MT | EMI Only | MT Only |
|---|---|---|---|
| Baseline | |||
| Diameter, mm | 3.7 ± 0.1 | 3.8 ± 0.2 | 4.1 ± 0.3 |
| Peak FV, cm/s | 100.9 ± 4.2 | 101.5 ± 5.0 | 102.1 ± 3.4 |
| FMD peak SR, s−1 | 265.2 ± 24.7 | 260.5 ± 22.7 | 258.3 ± 24.2 |
| Normalized FMD | 0.028 ± 0.003 | 0.030 ± 0.002 | 0.030 ± 0.003 |
| NTG dilation, % | ND | ND | ND |
| 90 minutes | |||
| Diameter, mm | 3.6 ± 0.1 | 3.8 ± 0.2 | 3.8 ± 0.2 |
| Peak FV, cm/s | 109.8 ± 7.8 | 105.2 ± 7.2 | 111.2 ± 4.9 |
| FMD peak SR, s−1 | 285.7 ± 25.7 | 269.6 ± 27.5 | 269.6 ± 27.5 |
| Normalized FMD | 0.032 ± 0.003† | 0.026 ± 0.002* | 0.037 ± 0.003† |
| NTG dilation, % | 15.7 ± 0.02 | 15.0 ± 0.02 | 14.9 ± 0.02 |
| 24 hours | |||
| Diameter, mm | 3.8 ± 0.1 | 3.8 ± 0.2 | 3.9 ± 0.3 |
| Peak FV, cm/s | 109.4 ± 6.6 | 108.8 ± 7.9 | 107.8 ± 6.5 |
| FMD peak SR, s−1 | 276.5 ± 27.7 | 266.0 ± 25.4 | 271.6 ± 25.6 |
| Normalized FMD | 0.031 ± 0.003† | 0.025 ± 0.002*† | 0.034 ± 0.003 |
| NTG dilation, % | 14.1 ± 0.03 | 15.1 ± 0.03 | 16.5 ± 0.03 |
| 48 hours | |||
| Diameter, mm | 3.7 ± 0.1 | 3.8 ± 0.2 | 3.9 ± 0.3 |
| Peak FV, cm/s | 109.6 ± 8.0 | 107.5 ± 8.9 | 109.1 ± 8.6 |
| FMD peak SR, s−1 | 275.3 ± 25.8 | 264.3 ± 27.7 | 274.6 ± 21.9 |
| Normalized FMD | 0.032 ± 0.003† | 0.025 ± 0.002*† | 0.034 ± 0.003 |
| NTG dilation, % | 14.2 ± 0.02 | 18.0 ± 0.02 | 15.6 ± 0.02 |
| 72 hours | |||
| Diameter, mm | 3.7 ± 0.1 | 3.9 ± 0.3 | 3.9 ± 0.3 |
| Peak FV, cm/s | 108.1 ± 8.7 | 106.6 ± 8.4 | 110.6 ± 6.9 |
| FMD peak SR, s−1 | 277.0 ± 27.9 | 251.6 ± 22.9 | 266.6 ± 21.8 |
| Normalized FMD | 0.026 ± 0.002 | 0.032 ± 0.003 | 0.028 ± 0.002 |
| NTG dilation, % | 15.6 ± 0.02 | 17.4 ± 0.03 | 14.4 ± 0.02 |
All values expressed as mean ± SE.
*
Significant differences observed in EMI only group versus MT only group (P < 0.05).
†
Significant within group differences observed from baseline.
FV, flow velocity; FMD, flow-mediated dilation; SR, shear rate; NTG, nitroglycerin; ND, not determined.