Figure 4.
Oriented cell protrusions direct EGF signaling in the leg disc epithelium. (A) Socket cells (purple) in the leg disc epithelium produce oriented protrusions that activate EGF signal transduction proximally and induce the bract fate in only one cell (brown) among the surrounding cells (light brown) that are competent to respond to EGF and develop into a bract. (B) A short, thick, pigmented and pointed structure called a bract is on the proximal side of Drosophila leg bristles.