Table 1.
Study subjects
| No exacerbation N = 13 (Asthma Index: 18.5; 11–22.5) | Exacerbation N = 17 (Asthma Index: 40; 31.8–52.3) | ALL N = 30 (Asthma Index: 30.5; 19.0–40.0) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Average Age | 28 | 29.7 | 28.9 | ||||||
| Sex (Female) | 8/13 (62%) | 13/17 (76%) | 21/30 (70%) | ||||||
| Viral Serology |
Rhinovirus: 9/13 Influenza A: 2/13 RSVB/ Coronavirus:1/13 Coronavirus: 1/13 |
Rhinovirus: 16/17 Influenza B: 1/17 |
Rhinovirus: 25 Influenza A: 2/30 Influenza B: 1/30 RSVB/ Coronavirus:1/30 Coronavirus: 1/30 |
||||||
| Acute | Baseline | Δ | Acute | Baseline | Δ | Acute | Baseline | Δ | |
| FEV1, L | 3.5 (2.8–3.9) | 3.4 (2.78–3.8) | 0.0 (− 0.1–0.08) | 3.3 (2.6–4.0) | 3.2 (2.5–3.9) | − 0.03 (−0.1–1.0) | 3.4 (2.6–3.9) | 3.3 (2.5–3.8) | −0.01 (−0.09–0.08) |
| FEV1, % predicted | 95.0 (82–101.8) | 92.0 (86.3–100.5) | − 0.6 (− 3.3–1.6) | 92.3 (88.5–103.5) | 93.0 (87.3–103.3) | − 0.4 (−3.7–1.9) | 92.5 (88–102.3) | 93.0 (88–102) | −0.6 (−3.3–1.8) |
| FEV1, L Post Albuterol | 3.7 (2.9–4.3) | 3.6 (2.8–4.3) | 0.01 (− 0.05–0.08) | 3.6 (2.7–4.1) | 3.4 (2.6–4.0) | 0.01 (−0.08–.1) | 3.7 (2.7–4.3) | 3.5 (2.7–4.2) | 0.01 (−0.08–0.09) |
| Modified Jackson Cold Scores | 9.5a (8.0–13.0) | 0.0 (0.0–3.0) | 9.5 (5–12) | 14.0a(10.5–14.3) | 0.0 (0–1.0) | 12.0 (8.8–14) | 11.5a (8–14) | 0.0 (0.0–2.0) | 10.5 (7–13) |
| Peak Flow | 441a (362.00–569) | 480 (409–588.5) | − 38b (− 64 to − 15.5) | 373a (288–430.5) | 468 (382.8–522.5) | − 76b (− 98.5 to −40.8) | 401a (316–506) | 471 (383–536) | −56.5 (−81 to –29) |
Data are shown as the median with interquartile range. Δ indicates the difference between acute and baseline visits.
Represents a difference with P < 0.005 between acute and baseline visits within the group.
On Δ represents the difference with P < 0.05 between no exacerbation and exacerbation.
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