Table 2.
Sputum cells during exacerbations
| No exacerbation (Asthma Index 0–29) | Exacerbation (Asthma Index ≥ 30) | Combined | ||||
|---|---|---|---|---|---|---|
| Acute | Baseline | Acute | Baseline | Acute | Baseline | |
| Eosinophil (Total) | 0.1 (0.0–0.2) | 0.0 (0.0–0.1) | 0.1a (0.0–0.4) | 0.0 (0.0–0.1) | 0.1 (0.0–0.3) | 0.0 (0.0–0.1) |
| Eosinophil, % | 0.5 (0.2–2.1) | 0.3 (0.0–1.3) | 0.5 (0.2–1.4) | 0.3 (0.0–0.5) | 0.5 (0.3–2.0) | 0.3 (0.0–0.8) |
| Neutrophil (Total) | 1.9 (0.8–4.6) | 2.2 (1.0–3.9) | 7.6a (3.2–25.6) | 1.6 (0.5–3.6) | 4.3 (1.2–8.7) | 2.0 (0.7–3.8) |
| Neutrophil, % | 32.0 (17.4–45.6) | 31.3 (17.0–43.0) | 49.8a (39.4–73.9) | 31.4 (18.9–50.2) | 43.1 (24–68.5) | 31.4 (17.0–46.7) |
| Lymphocyte (Total) | 0.1 (0.1–0.3) | 0.2 (0.0–0.4) | 0.4 (0.1–1.9) | 0.2 (0.1–0.3) | 0.3 (0.1–0.5) | 0.2 (0.1–0.3) |
| Lymphocytes, % | 2.5 (1.6–3.6) | 3.0 (0.9–5.5) | 2.9 (1.8–3.8) | 3.0 (1.8–4.7) | 2.7 (2.0–3.7) | 3.0 (1.5–5.0) |
| Macrophage (Total) | 4.3 (2.6–6.2) | 4.9 (2.3–7.6) | 4.3 (2.2–16.8) | 3.8 (2.5–6.1) | 4.3 (2.6–8.6) | 4.2 (2.5–6.5) |
| Macrophage, % | 65.0 (50.9–76.6) | 65.5 (51.9–80.0) | 43.5a (22.8–55.9) | 63.9 (44.2–73.0) | 53.1 (26.5–71.0) | 64.5 (46.2–74.8) |
Counts for the respective cell types are shown as total cells (number of cells ×105 per gram of sputum) or as percentage of white blood cells in sputum. Values are medians with interquartile range.
a
Represents a P < 0.05 in the difference between acute and baseline visits within the group.
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