Table 2.
Estimates (SE) of year 15 soluble adhesion molecules per quintile of averaged year 0/7 dietary pattern
| Quintile of Dietary Pattern Consumption | |||||||
|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | Ptrend1 | ||
| E selectin year 15 (35.1 (13.7)) | 446 | 514 | 576 | 643 | 639 | ||
| model 1 | 0 | −0.5 (0.8) | −1.3 (0.9) | −1.8 (0.9) | −4.2 (1.0) | <0.001 | |
| model 2 | 0 | −0.3 (0.8) | −0.7 (0.9) | −0.7 (0.9) | −2.4 (1.0) | 0.02 | |
| model 3 | 0 | −0.5 (0.8) | −0.8 (0.8) | −0.6 (0.9) | −1.8 (1.0) | 0.08 | |
| P selectin year 15 (36.8 (11.2)) | 471 | 537 | 611 | 682 | 646 | ||
| model 1 | 0 | −0.4 (0.7) | −2.0 (0.7) | −1.2 (0.7) | −3.4 (0.8) | <0.001 | |
|
A Priori
Diet Quality Score |
model 2 | 0 | −0.3 (0.7) | −1.7 (0.7) | −0.6 (0.7) | −2.6 (0.8) | 0.004 |
| model 3 | 0 | −0.4 (0.7) | −1.7 (0.7) | −0.6 (0.7) | −2.4 (0.8) | 0.009 | |
| sICAM-1 year 15 (154.7 (44.7)) | 464 | 531 | 603 | 674 | 639 | ||
| model 1 | 0 | −1.2 (2.7) | −5.6 (2.7) | −9.5 (2.8) | −21.2 (3.1) | <0.001 | |
| model 2 | 0 | −0.9 (2.6) | −4.3 (2.7) | −5.9 (2.8) | −15.1 (3.1) | <0.001 | |
| model 3 | 0 | −1.4 (2.6) | −4.3 (2.6) | −5.5 (2.7) | −12.9 (3.1) | <0.001 | |
| VCAM year 15 (525.8 (170.3)) | 417 | 541 | 618 | 657 | 665 | ||
| model 1 | 0 | −19.3 (10.1) | −32.4 (10.1) | −18.7 (10.6) | −45.4 (11.6) | 0.002 | |
| model 2 | 0 | −19.4 (10.2) | −32.1 (10.3) | −18.9 (11.0) | −45.1 (12.4) | 0.006 | |
| model 3 | 0 | −18.9 (10.2) | −31.9 (10.3) | −18.7 (11.0) | −45.5 (12.4) | 0.005 | |
|
| |||||||
| E selectin year 15 | 495 | 551 | 576 | 583 | 584 | ||
| model 1 | 0 | −0.8 (0.8) | −0.7 (0.8) | −1.3 (0.9) | −3.5 (0.9) | <0.001 | |
| model 2 | 0 | 0.0 (0.8) | 0.4 (0.8) | 0.4 (0.9) | −1.3 (1.0) | 0.03 | |
| model 3 | 0 | 0.0 (0.8) | 0.5 (0.8) | 0.5 (0.9) | −1.2 (1.0) | 0.02 | |
| P selectin year 15 | 524 | 585 | 600 | 619 | 619 | ||
| model 1 | 0 | −0.4 (0.7) | −0.6 (0.7) | −1.5 (0.7) | −2.2 (0.8) | 0.003 | |
| model 2 | 0 | 0.1 (0.7) | 0.1 (0.7) | −0.4 (0.7) | −0.8 (0.8) | 0.28 | |
| FV dietary pattern |
model 3 | 0 | 0.1 (0.7) | 0.2 (0.7) | −0.3 (0.7) | −0.8 (0.8) | 0.26 |
| sICAM-1 year 15 | 520 | 574 | 594 | 617 | 606 | ||
| model 1 | 0 | −5.9 (2.6) | −10.2 (2.7) | −14.7 (2.8) | −18.5 (3.0) | <0.001 | |
| model 2 | 0 | −2.2 (2.5) | −4.5 (2.6) | −5.8 (2.8) | −7.5 (3.1) | 0.02 | |
| model 3 | 0 | −2.2 (2.5) | −4.0 (2.6) | −5.3 (2.7) | −7.1 (3.0) | 0.01 | |
| VCAM year 15 | 547 | 609 | 595 | 627 | 620 | ||
| model 1 | 0 | −19.8 (9.9) | −30.7 (10.3) | −26.0 (10.8) | −25.0 (11.6) | 0.18 | |
| model 2 | 0 | −19.7 (9.9) | −30.7 (10.5) | −26.1 (11.2) | −24.8 (12.2) | 0.25 | |
| model 3 | 0 | −19.5 (10.0) | −30.5 (10.5) | −25.8 (11.2) | −24.6 (12.2) | 0.26 | |
|
| |||||||
| E selectin year 15 | 570 | 594 | 503 | 561 | 461 | ||
| model 1 | 0 | 1.3 (1.0) | 3.0 (1.2) | 5.5 (1.3) | 6.2 (1.5) | <0.001 | |
| model 2 | 0 | 0.2 (1.0) | 1.5 (1.2) | 3.6 (1.4) | 3.9 (1.5) | <0.001 | |
| model 3 | 0 | 0.7 (1.0) | 1.9 (1.2) | 3.5 (1.3) | 3.3 (1.5) | 0.001 | |
| P selectin year 15 | 600 | 633 | 637 | 693 | 484 | ||
| model 1 | 0 | 2.4 (0.8) | 3.8 (1.0) | 5.3 (1.1) | 5.7 (1.2) | <0.001 | |
| model 2 | 0 | 1.7 (0.8) | 2.9 (1.0) | 3.9 (1.1) | 4.1 (1.2) | 0.02 | |
| Meat dietary pattern |
model 3 | 0 | 1.9 (0.8) | 3.0 (1.0) | 3.9 (1.1) | 3.9 (1.2) | 0.02 |
| sICAM-1 year 15 | 599 | 625 | 634 | 581 | 472 | ||
| model 1 | 0 | 4.3 (3.3) | 12.7 (3.8) | 21.5 (4.4) | 26.7 (4.8) | <0.001 | |
| model 2 | 0 | −1.9 (3.2) | 3.9 (3.7) | 9.0 (4.3) | 11.9 (4.8) | 0.02 | |
| model 3 | 0 | −0.5 (3.1) | 4.9 (3.7) | 8.5 (4.2) | 9.8 (4.7) | 0.04 | |
| VCAM year 15 | 641 | 641 | 635 | 570 | 511 | ||
| model 1 | 0 | 10.1 (12.2) | −6.8 (14.4) | 14.8 (16.3) | 7.3 (18.2) | 0.73 | |
| model 2 | 0 | 10.5 (12.3) | −6.5 (14.6) | 16.2 (16.7) | 7.3 (18.8) | 0.67 | |
| model 3 | 0 | 9.9 (12.3) | −7.2 (14.7) | 15.7 (16.7) | 7.0 (18.8) | 0.67 | |
sICAM-1 soluble intercellular adhesion molecule 1, VCAM vascular cellular adhesion molecule 1
1
P-value for trend based on multivariate adjusted regression analysis with dietary pattern as a continuous value
Model 1: covariates include, race, sex, center, age, energy
Model 2: model 1 plus smoking status, educational attainment and physical activity
Model 3: model 2 plus BMI and waist