Table 3.

Biological process networks affected in E-embryos.

Biological process network	p-Value	# Molecules
Cluster #1
Cell death	3.85E−03	142
Cellular growth and proliferation — proliferation of cells	3.17E−03	117
Cell death — apoptosis	1.26E−02	107
Organismal survival — organismal death	6.00E−04	78
Organ morphology — morphology of organ	2.43E−03	69
Molecular transport — transport of molecule	3.63E−04	63
Cell cycle — cell cycle progression	1.23E−03	53
Cell death — cell survival	1.48E−02	52
Cellular function and maintenance — organization of cytoplasm	1.53E−03	50
Cell death — cell death of organ	5.48E−03	48
Cluster #2
Gene expression — transcription of DNA	1.19E−24	149
Gene expression — activation of DNA endogenous promoter	1.59E−21	111
Tissue development — tissue development	9.93E−16	198
Cell death	3.57E−07	196
Cellular growth and proliferation — proliferation of cells	4.36E−06	158
Embryonic development — organogenesis	2.66E−13	146
Organismal development — development of organ	1.72E−13	145
Cellular development — differentiation	3.00E−12	145
Organismal survival — organismal death	2.55E−09	115
Organ morphology — morphology of organ	2.62E−09	107
Cluster #3
Cell death	2.70E−02	38
Tissue development	5.98E−03	35
Gene expression — expression of RNA	7.12E−05	34
Cellular growth and proliferation — proliferation of cells	3.55E−02	31
Cellular development — differentiation	5.70E−03	27
Organismal survival — organismal death	5.68E−03	23
Cell cycle — cell cycle progression	2.47E−04	20
Neurological disease — encephalopathy	4.29E−03	20
Cellular function and maintenance — organization of cytoplasm	2.24E−03	17
Skeletal and muscular disorders — neuromuscular disease	8.00E−03	16