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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: J Mol Cell Cardiol. 2014 Feb 20;72:1–8. doi: 10.1016/j.yjmcc.2014.02.008

Figure 3. Transmural variation in Ca2+ sensitivity is disrupted in heart failure.

Figure 3

A) Mean values of normalized isometric tension plotted against pCa (= −log10[Ca2+]) for preparations from the three transmural regions of non-failing (left) and failing (right) hearts. Circles, squares, and triangles show data for sub-epicardial, mid-myocardial, and sub-endocardial preparations respectively. B) Symbols show the mean of the pCa50 values measured using 2 or 3 preparations from each region for each heart.