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. Author manuscript; available in PMC: 2014 May 28.
Published in final edited form as: PM R. 2013 Dec 22;6(5):427–436. doi: 10.1016/j.pmrj.2013.10.009

Table 1.

A representative sample of disorders associated with low bone mineral density in children

Primary bone disorders
 Osteogenesis imperfecta
 Fibrous dysplasia
 Hypophosphatasia
 Osteoporosis pseudoglioma syndrome
 Ehlers-Danlos syndrome
 Idiopathic juvenile osteoporosis
Secondary bone disorders
 Impaired mobility
  Cerebral palsy
  Spina bifida
  Spinal cord injury
  Traumatic brain injury
  Duchenne muscular dystrophy
Chronic inflammatory conditions
  Juvenile idiopathic arthritis
  Inflammatory bowel disease
  Systemic lupus erythematosus
Nutritional deficiencies and malabsorption
  Vitamin D deficiency
  Calcium deficiency
  Celiac disease
  Anorexia nervosa
  Liver failure
  Cystic fibrosis
Infiltrative disorders
  Leukemia
  Inborn errors of metabolism
Endocrinopathies
 Hypogonadism
 Hyperparathyroidism
 Hyperthyroidism
 Growth hormone deficiency
Medication-induced and iatrogenic effects
 Antiepileptics
 Chemotherapeutics
 Glucocorticoids
 Radiotherapy