Figure 6. shFkbp1b mediated knockdown of Fkbp1b validated at the protein level.
In vivo direct hippocampal shFkbp1b injection into one hemisphere (ipsilateral) is compared to the non-injected contralateral hemisphere. To validate knockdown at the protein level, immunohistochemical staining of FKBP11b/12.6 was performed. Arrow indicates injection site. Inset shows magnified view of CA1 region. (Modified from Gant et al., 2011)