Table 2.

Identity and Statistical Analysis of the 15 Treponema pallidum Genes Yielding the Highest Signal in a Chemiluminescent Immunoassay

Gene	Name	Sample number	Predicted protein size (kD)	Meana	St. dev	P value
TP0100	thioredoxin-like protein	20	—c	3709.2	294	<0.001
TP0163	ABC transporter (TroA, Tromp1)	32	—c	300.7	36	<0.001
TP0257	glycerophosphoryldiester phosphodiesterase (GlpQ)	46	—c	1447.7	94	<0.001
TP0298	exported protein TpN38	51	—c	277.7	16.5	<0.001
TP0319	membrane lipoprotein (TmpC)	59	—c	11259.1	452	<0.001
TP0326	outer membrane protein	61	—c	5017.7	550	<0.001
TP0435	lipoprotein, 17 kD (Tpp17)	79	—c	17765.6	2583	<0.001
TP0088	conserved hypothetical protein	18	23	572.4	49	<0.001
TP0133	hypothetical protein	24	43	1769.3	91	<0.001
TP0183	hypothetical protein	38	31	8338.6	705	<0.001
TP0307	conserved hypothetical protein	54	37	880.9	105	<0.001
TP0327b	hypothetical protein	62	20	214.1	58	0.198
TP0456b	hypothetical protein	80	47	265.7	102	0.023
TP0469	conserved hypothetical protein	85	54	444.4	69	<0.001
TP0470b	conserved hypothetical protein	86	43	294.7	101	0.0034

^aMean value units correspond to relative light units detected

^bGene identified as statistically insignificant

^cPredicted protein size was not included for previously characterized genes