Table 2.
Annotation of 12 of the 50 NMF Basis Vectors Based on the MIPS Functional Categories
| 1 | +1 amino-acid metabolism (204 ORFs) [82] | 687 |
| +2 nitrogen and sulphur metabolism (74 ORFs) [27] | ||
| +81 stress response (169 ORFs) [43] | ||
| -34 ribosomal proteins (206 ORFs) [98] | ||
| -35 translation (62 ORFs) [22] | ||
| -92 organization of cytoplasm (557 ORFs) [163] | ||
| 3 | +1 amino-acid metabolism (204 ORFs) [21] | 141 |
| 4 | +81 stress response (169 ORFs) [9] | 53 |
| 8 | +21 pheromone response, mating-type det., sex-spec. proteins (159 ORFs) [24] | 211 |
| -4 phosphate metabolism (31 ORFs) [3] | ||
| 9 | +5 C-compound and carbohydrate metabolism (413 ORFs) [115] | 1007 |
| +15 metabolism of energy reserves (glycogen, trehalose) (37 ORFs) [21] | ||
| +47 C-compound and carbohydrate transporters (46 ORFs) [23] | ||
| -1 amino-acid metabolism (204 ORFs) [53] | ||
| 17 | +1 amino-acid metabolism (204 ORFs) [40] | 203 |
| +15 metabolism of energy reserves (glycogen, trehalose) (37 ORFs) [14] | ||
| -29 rRNA transcription (104 ORFs) [17] | ||
| 19 | +13 respiration (85 ORFs) [18] | 155 |
| +100 mitochondrial organization (364 ORFs) [27] | ||
| -1 amino-acid metabolism (204 ORFs) [18] | ||
| 20 | +34 ribosomal proteins (206 ORFs) [29] | 207 |
| +46 ion transporters (76 ORFs) [13] | ||
| +88 homeostasis of cations (112 ORFs) [17] | ||
| +100 mitochondrial organization (364 ORFs) [53] | ||
| -1 amino-acid metabolism (204 ORFs) [18] | ||
| -34 ribosomal proteins (206 ORFs) [24] | ||
| -35 translation (62 ORFs) [7] | ||
| -92 organization of cytoplasm (557 ORFs) [40] | ||
| 23 | +11 tricarboxylic-acid pathway (23 ORFs) [4] | 128 |
| +15 metabolism of energy reserves (glycogen, trehalose) (37 ORFs) [6] | ||
| -4 phosphate metabolism (31 ORFs) [3] | ||
| 36 | +29 rRNA transcription (104 ORFs) [41] | 557 |
| -5 C-compound and carbohydrate metabolism (413 ORFs) [77] | ||
| -11 tricarboxylic-acid pathway (23 ORFs) [10] | ||
| -15 metabolism of energy reserves (glycogen, trehalose) (37 ORFs) [14] | ||
| 42 | +1 amino-acid metabolism (204 ORFs) [40] | 199 |
| +6 lipid, fatty-acid and isoprenoid metabolism (210 ORFs) [21] | ||
| +81 stress response (169 ORFs) [22] | ||
| -21 pheromone response, mating-type det., sex-spec. proteins (159 ORFs) [11] | ||
| 43 | +5 C-compound and carbohydrate metabolism (413 ORFs) [126] | 1111 |
| +10 pentose-phosphate pathway (9 ORFs) [7] | ||
| +11 tricarboxylic-acid pathway (23 ORFs) [17] | ||
| +81 stress response (169 ORFs) [64] | ||
| -29 rRNA transcription (104 ORFs) [58] | ||
| -34 ribosomal proteins (206 ORFs) [87] |
Each annotation includes a plus or minus sign (indicating whether expression is enhanced or decreased compared with control experiments), an integer number indexing the MIPS category, the name of the MIPS category, the number of ORFs belonging to the MIPS category, and the number of genes in the basis vector belonging to the MIPS category (in square brackets). The third column indicates the number of genes that are non-zero in this basis vector. The full set of 50 basis vectors is provided as supplementary information