Table I.

Physical Stability of Cationic Niosomes Formulated with Span 20/Cholesterol/Spermine-Cationic Lipid in a Molar Ratio of 2.5:2.5:1 After Storage at 4°C and 25°C for 30 Days. Each Value Represents the Mean ± Standard Deviation (S.D.) from Three Independent Experiments

Formulations	Particle size (nm)			Zeta potential (mV)
	Initial (day 0)	Day 30		Initial (day 0)	Day 30
		4°C	25°C		4°C	25°C
Niosomes-C14 (Span 20/Cho/spermine-C14)	876 ± 25	893 ± 14	2,459 ± 348	+42 ± 7	+38 ± 5	+1 ± 3
Niosomes-C16 (Span 20/Cho/spermine-C16)	462 ± 10	472 ± 2	2,130 ± 744	+49 ± 1	+47 ± 2	+2 ± 2
Niosomes-C18 (Span 20/Cho/spermine-C18)	385 ± 12	395 ± 3	2,796 ± 616	+54 ± 1	+53 ± 3	+15 ± 1