Table VI.
Calculation of Azithromycin Dose Number for Individual Patients Reported in Nahata et al. (21)
| Subject | Age (years) |
Weight (kg) |
Height (cm) | BSA-derived volume (ml) | Dose (mg) |
Dose number |
|---|---|---|---|---|---|---|
| 1 | 2.3 | 13.0 | 88.0 | 81.5 | 60 | 0.15 |
| 2 | 2.1 | 12.5 | 87.5 | 79.7 | 60 | 0.15 |
| 3 | 2.3 | 13.0 | 88.0 | 81.5 | 60 | 0.15 |
| 4 | 5.0 | 18.0 | 108 | 106 | 80 | 0.15 |
| 5 | 3.9 | 16.0 | 101 | 96.8 | 80 | 0.17 |
| 6 | 1.9 | 12.5 | 86.5 | 79.2 | 60 | 0.15 |
| 7 | 2.0 | 12.7 | 87.0 | 80.1 | 60 | 0.15 |
| 8 | 1.7 | 12.0 | 84.0 | 76.5 | 60 | 0.16 |
| 9 | 1.1 | 10.6 | 77.0 | 68.8 | 60 | 0.17 |
| 10 | 1.4 | 11.5 | 81.0 | 73.5 | 60 | 0.16 |
| 11 | 1.5 | 11.7 | 82.0 | 74.6 | 60 | 0.16 |
| 12 | 0.5 | 8.0 | 67.0 | 55.8 | 40 | 0.14 |
| 13 | 2.4 | 13.50 | 90.5 | 84.2 | 80 | 0.19 |
Subject age and dose were obtained from the article. Weight and height were determined from the CDC growth chart for boys, which were then used to calculate BSA-derived pediatric reference volume. Dose numbers for each infant and child indicates high solubility, in agreement with the more general approach (Table V)