Table VIII.
Calculation of Ciprofloxacin Dose Number for Individual Patients Reported in Schaefer et al. (22)
| Subject | Age (years) |
Weight (kg) |
Height (cm) | BSA-derived volume (ml) | Dose (mg) |
Dose number |
|---|---|---|---|---|---|---|
| 1 | 9.3 | 29 | 135 | 151 | 551 | 24.4 |
| 2 | 12.0 | 42 | 149 | 191 | 714 | 25.0 |
| 3 | 10.3 | 28.8 | 140 | 153 | 547 | 24.0 |
| 4 | 10.5 | 26.9 | 141 | 148 | 538 | 24.1 |
| 5 | 9.30 | 18 | 135 | 119 | 432 | 24.3 |
| 6 | 15.7 | 37 | 173 | 193 | 629 | 21.8 |
| 8 | 14.7 | 41 | 169 | 201 | 697 | 23.2 |
| 10 | 6.8 | 19 | 120 | 115 | 456 | 26.4 |
Subject age, weight, and dose were obtained from the article. Height was determined from the CDC growth chart for boys, which was then used to calculate BSA-derived pediatric reference volume. Dose numbers for each child and adolescent indicates low solubility, in agreement with the more general approach (Table VII)