Table IX.

Summary of Pediatric BCS Classification and Comparison to Adult BCS Classification

Drug	Adult BCS Class	Pediatric BCS Classa
Dolasetron	1	3
Ketoprofen	2	4b
Voriconazole	2	4c
Azithromycin	3	3
Ciprofloxacin	4	4d

^aIt should be noted that the permeability class contribution was elucidated from literature pharmacokinetic data that did not include all pediatric subpopulations (i.e., did not include neonates, infants, children, and adolescents)

^bHowever, neonates are calculated to be high solubility (i.e., Class 3) using Young’s rule, Clark’s rule and Modified Weight Rule. Infants are calculated to be high solubility (i.e., Class 3) using Young’s rule and Clark’s rule

^cHowever, neonates are calculated to be high solubility (i.e., Class 3) using Young’s rule and Clark’s rule. Infants are calculated to be high solubility (i.e., Class 3) using Young’s rule

^dHowever,Young’s rule for neonates indicates high solubility (i.e., Class 3)