Table 2.
Levels of pro- and anti-inflammatory cytokines in severe and moderate trauma and in control group immediately after trauma (t1)
| Cytokines | Moderately injured (n = 31) | Severely injured (n = 27) | Controls (n = 13) | ANOVA | |||
|---|---|---|---|---|---|---|---|
| M | SE | M | SE | M | SE | F (2,68) | |
| IL-1β | 16.4 | 10.3 | 28.3 | 25.0 | 0.8 | 0.4 | 0.3 |
| IL-2 | 53.2 | 13.8 | 63.0 | 42.9 | 61.6 | 17.5 | 2.4 |
| IL-6 | 39.6 | 9.1 | 83.9 | 37.5 | 5.0 | 3.4 | 7.2* |
| IL-8 | 118.5 | 51.4 | 161.6 | 46.0 | 12.2 | 4.3 | 6.5* |
| IL-12 | 24.1 | 16.9 | 7.6 | 4.3 | 19.1 | 8.6 | -1.2 |
| IFN-γ | 40.4 | 11.3 | 64.1 | 15.2 | 47.2 | 14.9 | 0.1 |
| TNF-α | 23.0 | 21.3 | 8.5 | 5.0 | 11.9 | 6.4 | 0.6 |
| IL-4 | 14.3 | 4.6 | 20.1 | 9.9 | 32.4 | 6.0 | 6.1* |
| IL-10 | 1.8 | 0.7 | 16.4 | 13.6 | 4.9 | 2.3 | 1.2 |
| TGF-β | 23.6 | 4.8 | 22.4 | 4.4 | 13.7 | 3.3 | 1.7 |
* p < 0.01
ANOVA was conducted for log transformed measures
Levels of cytokines are presented in pg/ml, except for TGFβ presented in ng/ml