Table 4.
Biased Amino Acid Substitutions in the Orthologous Genes of C. glutamicum and C. efficiens
| C. glutamicum | C. efficiens | Forward | Reverse | Pointa | G + C changing by one-base substitution |
|---|---|---|---|---|---|
| Lys | Arg | 2855 | 664 | 1095.5 | AAA → AGA, AAG → AGG |
| Ser | Ala | 3378 | 2372 | 503 | TCA → GCA, TCC → GCC, TCG → GCG, TCT → GCT |
| Ser | Thr | 2623 | 1723 | 450 | |
| Ile | Val | 4332 | 3585 | 373.5 | ATA → GTA, ATC → GTC, ATT → GTT |
| Asn | Arg | 978 | 372 | 303 | |
| Gln | Glu | 1321 | 747 | 287 | |
| Ile | Leu | 2191 | 1642 | 274.5 | ATA → CTA, ATC → CTC, ATT → CTT |
| Ser | Gly | 1013 | 610 | 201.5 | AGC → GGC, AGT → GGT |
| Lys | Thr | 600 | 235 | 182.5 | AAA → ACA, AAG → ACG |
| Ala | Pro | 1019 | 656 | 181.5 |
a
Point is defined as the difference between the number of amino acid substitutions from C. glutamicum to C. efficiens and the number of substitutions in the opposite direction, divided by 2. All of the asymmetrical amino acid substitutions showed probability of obtaining the observed deviation from 50:50 by chance less than 0.001