Table 6. Association status of common haplotypes of TLR4 gene with DR.
| Haplotype | Frequency | Case, control frequencies | Chi square | p value |
|---|---|---|---|---|
| ACATC |
0.375 |
0.374, 0.379 |
0.019 |
0.89 |
| ACATT |
0.148 |
0.155, 0.120 |
1.363 |
0.243 |
| ACGTC |
0.074 |
0.073, 0.081 |
0.135 |
0.713 |
| ACACC |
0.039 |
0.038, 0.042 |
0.06 |
0.806 |
| ACGCT |
0.045 |
0.041, 0.060 |
1.235 |
0.266 |
| ATATC |
0.044 |
0.043, 0.045 |
0.012 |
0.912 |
| GCATC |
0.037 |
0.041, 0.023 |
1.34 |
0.247 |
| GCGTT |
0.018 |
0.019, 0.013 |
0.29 |
0.589 |
| ACACT |
0.052 |
0.052, 0.053 |
0.004 |
0.953 |
| ATACT |
0.014 |
0.013, 0.019 |
0.349 |
0.555 |
| ACGTT |
0.043 |
0.041, 0.049 |
0.218 |
0.641 |
| ACGCC |
0.024 |
0.023, 0.029 |
0.254 |
0.614 |
| ATGCT |
0.01 |
0.009, 0.016 |
0.717 |
0.397 |
| GCACT | 0.02 | 0.019, 0.024 | 0.164 | 0.685 |
Fourteen haplotypes with a frequency of more than 1% was found.