Table 1.
Statistical Summary of E. coli Search Results
Namea | Lengthb | Number of examplesc | Information score “hits”d | QPMEME “hits”e | Significancef |
---|---|---|---|---|---|
ArcA | 15 | 14 | 391 | 52 | 6.3 |
ArgR | 18 | 17 | 320 | 79 | 8.9 |
CRP | 22 | 49 | 3093 | 796 | 27.2 |
CytR | 18 | 5 | 745 | 42 | 4.3 |
DnaA | 15 | 8 | 98,748 | 461 | 0.5 |
FadR | 17 | 7 | 28 | 10 | 9.0 |
FarR | 10 | 4 | 1893 | 241 | 3.7 |
FIS | 35 | 19 | 7687 | 255 | 4.1 |
Fnr | 22 | 14 | 174 | 36 | 13.9 |
FruR | 16 | 12 | 31 | 23 | 14.8 |
GalR | 16 | 7 | 10 | 9 | 8 × 103 |
GevA | 20 | 4 | 15 | 5 | 5 × 103 |
GlpR | 20 | 13 | 9132 | 192 | 1.6 |
H-NS | 11 | 15 | 14,619 | 2340 | 2.7 |
IHF | 48 | 26 | 82,494 | 359 | 13.6 |
LexA | 20 | 19 | 39 | 39 | 104 |
LRP | 25 | 12 | 90,676 | 4087 | 32.9 |
MalR | 10 | 10 | 96 | 61 | 8.7 |
MetJ | 16 | 15 | 404 | 42 | 1.6 |
MetR | 15 | 8 | 344 | 26 | 3.2 |
NagC | 23 | 6 | 72 | 8 | 7.0 |
NarL | 16 | 11 | 2090 | 19 | 7.5 |
OmpR | 20 | 9 | 4890 | 93 | 2.6 |
PhoB | 22 | 15 | 258 | 23 | 14.8 |
PurR | 26 | 22 | 47 | 28 | 27.0 |
σ70 (15) | 27 | 27 | 11,517 | 635 | 2.2 |
σ70 (16) | 28 | 48 | 15,867 | 912 | 2.6 |
σ70 (17) | 29 | 116 | 41,488 | 3923 | 0.6 |
σ70 (18) | 30 | 34 | 10,133 | 381 | 0.6 |
σ70 (19) | 31 | 25 | 15,086 | 301 | 0.4 |
σ54 | 16 | 6 | 16 | 7 | 6.0 |
σs | 29 | 15 | 10,669 | 245 | 2.0 |
SoxS | 35 | 14 | 3963 | 49 | 2.2 |
TyrR | 22 | 17 | 3843 | 73 | 6.2 |
See Web site http://www.biomaps.rutgers.edu/bioinformatics/QPMEME.htm. for details.
TF name. Note σ70 (15), etc., refers to σ70 sites with 15 bp spacer between −10 and −35 boxes.
length of the binding site in bp.
number of known binding sites used to determine ε, μ parameters.
number of candidate sites found using information theoretic weight matrix with threshold set to include most of the example sites (the 2σ cut-off; Robison et al. 1998).
number of candidate sites found using QPMEME approach.
“Significance” defined here as a difference between actual and expected number of sites normalized to the square root of the expected number.