Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Half-lives of type II’ turn peptides treated with Pronase E*
| t1/2 (min) | ||
|---|---|---|
| Peptide | U | C |
| Scramble** | 3 (± 5) | -- |
| HB-pG | 15 (± 5) | 280 (± 5) |
| NHB-pG | 20 (± 5) | No observable degradation*** |
| Term-pG | 60 (± 5) | > 300 |
Reactions carried out in 10 mM sodium phosphate, 140 mM NaCl, pH 7.6 with 500 µM peptide at 37 °C.
Scrambled sequence: Ac-pQVIKRGOWW(Pra)(AzK)VK-NH2
Over a 48 hour time period
