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. 2014 May 11;2014:807874. doi: 10.1155/2014/807874

Figure 2.

Figure 2

ER stress induces FGF21 secretion. Differentiated 3T3-L1 cells were treated with 100 nM TG for 0, 2, 4, 8, 16, and 24 h (a); or different concentrations of TG for 24 h (b), at the end of treatment, cell culture medium was collected. The protein level of FGF21 was determined by ELISA. Values are mean ± S.E. of three independent experiments. Statistical significance relative to vehicle control: *P < 0.05; ***P < 0.001.