. 2003 Nov;13(11):2396–2405. doi: 10.1101/gr.1198103

Table 1.

A Priori Unidentifiable Parameters Grouped by Biological Function, for the Three Perturbations

Biological function (total params.)	Single step	Single pulse	Double pulse
Protein monomer degradation (10)	8 (6)^a	4 (2)^a	4 (2)^a
Transcript degradation (10)	7	5	5
Translation (10)	9 (7)^a	5 (3)^a	6 (4)^a
Unidimerization and dimer deg. (21)	13 (6)^b	10 (3)^b	11 (4)^b
Promoter un/binding (20)	12 (2)^b	13 (3)^b	13 (3)^b
Transcription (26)	2	0	0
Total (97)	51 (30)^c (23)^d	37 (16)^c (11)^d	39 (18)^c (13)^d

The number of unidentifiable parameters that would remain if the insensible parameters (see text) were removed from the model.

The number of unidentifiable parameters that would remain if the equilibrium approximation was made for the appropriate parameters.

The total remaining unidentifiable parameters if the insensible parameters were removed and the equilibrium assumption was applied where appropriate.

The total remaining unidentifiable parameters if mRNA half-lives were measured in addition to application of the equilibrium assumption and removal of insensible parameters.