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Histopathological examination (patient #7). (a) Before treatment with imiquimod 5% cream (baseline): actinic elastosis is present. No signs of actinic keratosis are recognizable. (b) During treatment with imiquimod 5% cream (day 15): note the early stage of actinic keratosis (AK 1). (c) 4 weeks after treatment with imiquimod 5% cream (week 8): no signs of actinic keratosis can be observed.
