Table 5. Number and percentage of different types of chromosomal aberration in bone marrow in different experimental groups.
Groups | TCA |
No. and percentage (%) of metaphases |
|||||
Including gaps | Excluding gaps | Chromatide gap | Break and fragment | Deletion | More than one aberration | Polyploidy | |
Normal control | 3.40±0.25 | 1.80±0.20 | 8 (1.6) | 4 (0.8) | 2 (0.4) | - | 3 (0.6) |
Cisplatin control | 13.20±0.97c | 9.20±1.06b | 20 (4.0) | 27 (5.4) | 6 (1.2) | 7 (1.4) | 6 (1.2) |
Avocado extract | 8.00±0.73bd | 5.40±0.38ad | 13 (2.6) | 15 (3.0) | 4 (0.8) | 3 (0.6) | 5 (1.0) |
E. sativa extract | 6.60±0.25ad | 4.60±0.51ad | 10 (2.0) | 13 (2.6) | 3 (0.6) | 3 (0.6) | 4 (0.8) |
Flaxseed extract | 7.40±0.39ad | 4.60±0.25ad | 14 (2.8) | 10 (2.0) | 7 (1.4) | 4 (0.8) | 2 (0.4) |
Walnut extract | 6.80±0.60bd | 4.20±0.38ad | 13 (2.6) | 11 (2.2) | 3 (0.6) | 2 (0.4) | 5 (1.0) |
Values of TCA are expressed as mean±SE. When all groups were compared with normal control, asignificant at 0.05 level, bsignificant at 0.01 level, csignificant at 0.001 level. When test groups were compared with cisplatin control: dsignificant at P<0.001. TCA: total chromosomal aberrations.