The model metabolic pathway used in these studies. Solid arrows represent mass flow, dashed arrows represent kinetic regulation; arrow ends represent activation, blunt ends inhibition. S and P are the pathway substrate and product and are held at constant concentrations; M1 and M2 are intermediate metabolites of the pathway; E1, E2, and E3 are the enzymes; G1, G2, and G3 are the mRNA species for the enzymes.