Table 1.
Association of HLA Class II DQ Haplotypes and Presence of GAD65Ab(DPD)
| Association With Autoimmune T1D | DPD-negative (n = 65) | DPD-positive (n = 152) | P Value | |
|---|---|---|---|---|
| DQA1*0301/DQB1*0302 | Susceptibility | 51% (33/65) | 30% (48/152) | .006 |
| DQA1*0301/DQB1*0201 | Susceptibility | 30% (19/65) | 15% (23/152) | .014 |
| DQA1*0501/DQB1*0201 | Susceptibility | 27% (17/62) | 29% (45/152) | NS |
| DQA1*0401/DQB1*0402 | Susceptibility | 10% (7/65) | 16% (25/152) | NS |
| DQA1*0101/DQB1*0501 | Susceptibility | 14% (9/62) | 18% (28/152) | NS |
| DQA1*0102/DQB1*0602 | Resistance | 8% (5/62) | 10% (16/152) | NS |
Abbreviation: NS, not significant.