Table 1.

Temporal cytokine and chemokine production in TK^+/+ and TK ^−/− BAL fluid after LPS-induced lung injury

Genotype	Cytokine (ng/mL)	0 h	1 h	2 h	4 h
TK+/+	IL-6	0.002 ± 0.002	0.65 ± 0.022	2.41 ± 0.35	1.05 ± 0.37
	MIP-2	0.34 ± 0.082	8.6 ± 3.7	7.9 ± 0.56	4.6 ± 1.01
	IFN-γ	0.053 ± 0.007	0.035 ± 0.014	0.047 ± 0.0076	0.063 ± 0.010
	MCP-1	0.02 ± 0.001	0.047 ± 0.018	0.373 ± 0.057	0.087 ± 0.038
TK−/−	IL-6	0.05 ± 0.05	0.47 ± 0.16	1.31 ± 0.23*	1.17 ± 0.124
	MIP-2	0.30 ± 0.14	5.5 ± 0.79	7.3 ± 1.47	4.8 ± 0.48
	IFN-γ	0.088 ± 0.006	0.038 ± 0.020	0.030 ± 0.011	0.044 ± 0.010
	MCP-1	0.04 ± 0.032	0.042 ± 0.007	0.182 ± 0.060*	0.280 ± 0.232

^*P < 0.05 compared with the wild-type treated group at the same time point.