Table 2.
The Allelic Gene Expression Ratios for Seven Genes in Multiple Tissues Measured by Quantitative PCR
| Genes | SNP ID | Liver | Kidney | Heart | Othera | No. of fetuses |
|---|---|---|---|---|---|---|
| ZIM2b | rs3143 | >8.0 | >8.0 | >8.0 | >8.0 | 3 |
| SNRPNb | rs705 | >8.0 | >8.0 | >8.0 | >8.0 | 3 |
| TAP2b | rs17034 | 3.22 ± 1.57 | 1.90 ± 0.88 | 4.67 ± 2.88 | 2.19 ± 0.89 | 7 |
| ELAC2b | rs2523 | 2.33 ± 0.87 | 2.55 ± 0.54 | 2.92 ± 0.73 | 2.86 ± 0.52 | 7 |
| DKFZP727G051b | rs1837 | 2.80 ± 1.05 | 2.32 ± 0.53 | 2.16 ± 0.41 | 2.05 ± 0.43 | 7 |
| UGDH | rs1450 | 1.53 ± 0.72 | 1.44 ± 0.29 | 1.39 ± 0.14 | 1.49 ± 0.35 | 3 |
| C11orf23 | rs1996 | 1.52 ± 0.27 | 1.38 ± 0.39 | 1.52 ± 0.29 | 1.22 ± 0.16 | 2 |
The values are the ratios (allele A/allele B) between the two alleles. The values were inverted if less than one (allele B/allele A, when allele B was preferentially expressed). The mean ± SD is provided for allelic gene expression in the various tissues
Several different fetal tissues were used, including adrenal, limb, and lung
Allelic difference in gene expression is significantly deviated from equal expression (95% confidence interval). The confidence interval was generated from heterozygous DNAs