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Simulation of the effect of decay rate on gene induction. Equation 6 (Methods) was solved for a step function RNA synthesis impulse: the synthesis rate was increased from 1 copy/(min · cell) to 100 copies/(min · cell) from 50–550 min. Using the indicated first-order decay constant (in units of 1/minute), the steady-state concentration of RNA was calculated and divided by initial concentration to determine the fold induction.
