Table 2. Clinicopathological characteristics of the patients.
Gender | |
Male | 41 |
Female |
19 |
Age at diagnosis, years | |
Mean | 61, 58 |
Range |
44–81 |
Site | |
Oral cavity | 7 |
Oropharynx | 30 |
Hypopharynx | 9 |
Larynx | 9 |
Nasopharynx | 1 |
Carcinoma of unknown primary (CUP) | 3 |
Other |
1 |
Tumour size | |
T0 | 3 |
T1 | 1 |
T2 | 13 |
T3 | 11 |
T4a | 26 |
T4b |
6 |
Nodal stage | |
N0 | 5 |
N1 | 7 |
N2a | 3 |
N2b | 26 |
N2c | 17 |
N3 |
2 |
Stage (UICC) | |
I | 0 |
II | 1 |
III | 7 |
Iva | 41 |
IVb |
7 |
p16 Expression | |
No p16 expression | 29 |
Focal p16 expression | 8 |
Moderate diffuse p16 expression | 6 |
High diffuse p16 expression |
17 |
Chemotherapy | |
MMC/5-FU | 45 |
Cisplatin/5-FU | 7 |
MMC/Cetuximab | 1 |
Other |
7 |
Radiotherapy | |
Treated | 60 |
Range of the total doses (Gy) |
66–70 |
Response to the primary therapy | |
Responder | 36 |
Non-responder |
24 |
Recurrence | |
No recurrence | 43 |
Recurrence | 13 |
Abbreviations: 5-FU=5-fluorouracil; MMC=mitomycin C; UICC=Union for International Cancer Control.