Table 2. MRI characteristics of temporal lobe necrosis.
| Characteristic | 2D-RT group | IMRT group | P-value |
|---|---|---|---|
|
WMLs | |||
| Temporal lobes (number) | 128 out of 128 (100%) | 48 out of 50 (94.44%) | 0.078a |
| Size (mm) |
40.9 |
37.3 |
0.326b |
| Severity of WMLs |
|
|
< 0.001a |
| Mild | 53 out of 128 (41.4%) | 36 out of 48 (75.0%) | |
| Moderate | 34 out of 12863 (26.6%) | 9 out of 48 (18.8%) | |
| Severe |
41 out of 128 (32.0%) |
3 out of 48 (6.3%) |
|
|
Contrast-enhanced lesions | |||
| Temporal lobes (number) | 123 out of 128 (96.1%) | 47 out of 50 (94.0%) | 0.688a |
| Size (mm) |
22.4 |
15.6 |
< 0.001b |
| Pattern of peripheral enhancement |
|
|
0.001c |
| Spreading wavefront | 102 out of 123 (82.9%) | 28 out of 47 (59.6%) | |
| Nodular |
21 out of 123 (17.1%) |
19 out of 47 (40.4%) |
|
| Pattern of interior enhancement |
|
|
0.091c |
| Swiss cheese/soap bubble | 85 out of 123 (69.1%) | 26 out of 47 (55.3%) | |
| Solid |
38 out of 123 (30.9%) |
21 out of 47 (44.7%) |
|
| Number of enhancing lesions |
|
|
0.129c |
| Single lesion | 68 out of 123 (55.3%) | 32 out of 47 (68.1%) | |
| Multiple lesions |
55 out of 123 (44.7%) |
15 out of 47 (31.9%) |
|
| Location in the mediolateral direction |
|
|
< 0.001c |
| Located within the medial 1/3 | 15 out of 123 (12.2%) | 21 out of 47 (44.7%) | |
| Between the medial 1/3 and lateral 1/3 | 33 out of 123 (26.8%) | 18 out of 47 (38.3%) | |
| Spread to the lateral 1/3 |
75 out of 123 (61.0%) |
8 out of 47 (17.0%) |
|
| Location in the superoinferior direction |
|
|
0.009a |
| Located within the inferior 1/3 | 11 out of 123 (8.9%) | 8 out of 47 (17.0%) | |
| Between the inferior 1/3 and superior 1/3 | 88 out of 123 (71.6%) | 38 out of 47 (80.9%) | |
| Spread to the superior 1/3 |
24 out of 123 (19.5%) |
1 out of 47 (2.1%) |
|
|
Cysts | |||
| Temporal lobes (number) | 10 out of 128 (7.8%) | 1 out of 50 (2%) | 0.185a |
| Size (mm) |
30.9 |
19.8 |
0.619b |
| Local mass effect |
|
|
0.095a |
| None | 71 out of 128 (55.5%) | 37 out of 50 (74.0%) | |
| Sulci | 24 out of 128 (18.8%) | 6 out of 50 (12.0%) | |
| Sulci and ventricle | 25 out of 128 (19.5%) | 4 out of 50 (8.0%) | |
| Sulci, ventricle and midline | 8 out of 128 (6.3%) | 3 out of 50 (6.2%) | |
Abbreviations: 2D-RT=two-dimensional radiotherapy; IMRT=intensity-modulated radiotherapy; MRI= magnetic resonance imaging; WML=white-matter lesion.
a
P-values calculated by Fisher's exact test.
b
P-values calculated by the independent-samples t-test.
c
P-values calculated by the χ2-test.