Figure 2. Integrative network analysis.
MetaCore network analysis integrating both gene data (red circles) and protein data (blue circles) into regulatory sub-networks active in the response of MLO-Y4 cells to OFF. The inferred central transcription factors c-Myc (p=2.09×10−7), c-Jun (p=1.82×10−6), and RelA/NF-κB (p=8.39×10−6) are the most significantly over-connected to the observed dataset.