Table I.
GCS expression in human breast cancer.
Tumors | GCS mRNA levels (mean ± SD, copies) | Overexpressed/total cases (>307 copies) |
---|---|---|
Stage I | 243±56 | 1/3 |
Stage II | 222±41 | 3/6 |
Stage III | 325±48 | 5/7 |
LN-negative | 138±12 | 2/8 |
LN-positive | 408±37a | 7/8 |
ER-negative | 49±8 | 0/7 |
ER-positive | 367±38a | 7/9 |
The value of mean ± 2SD in normal breast tissues (307 copies) was used to evaluate the overexpression of GCS mRNA in specimens. LN, lymph node; ER, estrogen receptor.
p<0.001 compared with LN-negative or ER-negative.