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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2014 Jan;73(1):72–80. doi: 10.1097/NEN.0000000000000028

Figure 1.

Figure 1

Examples of severity scores given to plaque densities (top) and white matter rarefaction (WMR- bottom). Top: 80 µm sections of the superior frontal gyrus stained with the Campbell Switzer enhanced silver stain -from left to right: 0 - none, 1 - mild, 2 - moderate, and 3 - frequent plaque densities. Bottom: macro view of 80 µm sections of the frontal lobe stained with hematoxylin and eosin, WMR was scored as from left to right: 0 - none, 1 - mild, 2 - moderate, and 3 - severe. In this study, a case was defined as having significant WMR if it had a score of 2 or higher in one or more of the following lobes: frontal, parietal, temporal and occipital.