Table 4. Comparative inhibition data for human and murine 1ip-hydroxysteroid dehydrogenase types 1 and 2.

Inhibitor	hHSD1	hHSD2	mHSD1	mHSD2	Ref.
12	Ki = 7 nM	26,000	Ki = 4 nM	>100,000	[36]
13	6	18,000	4	55,000	[37]
20	3	–	53	–	[42]
22	26	–	10 and 42†	–	[56]
23	10	–	10	–	[48]
28	Ki = 1.4 nM	–	Ki = 0.63 nM	–	[52]

Unless otherwise stated the Inhibition data are IC₅₀ values expressed as nM.

^†Two IC₅₀ values are given for 22 with mHSDI.

h: Human; HSD: Hydroxysteroid dehydrogenase; m: Murine.