Table 1.
Inhibitory effect of 4-HNE on the cell proliferation of DU145 and LNCaP cells
| 4-HNE (µmol/l) | DU145 | LNCaP | ||
|---|---|---|---|---|
| 24 h | 48 h | 24 h | 48 h | |
| 20 | 0.32% | 2.73% | 10.19% | 12.03% |
| 40 | 2.93% | 1.04% | 19.46% | 26.77% |
| 60 | 3.08% | 1.13% | 22.81% | 50.12% |
| 80 | 2.82% | 1.49% | 28.07% | 61.85% |
| 100 | 2.15% | 1.38% | 34.22% | 70.45% |
Cell proliferation evaluated by MTT assay in DU145 and LNCaP cells untreated or treated with 20, 40, 60, 80 or 100 µM 4-HNE. The results shown were the mean of three parallel experiments (triplicate wells) for each concentration point.