Table 2.
Correlation of KIF gene expression with taxane response in the MDACC data set
| Gene | Coefficient* | p-value |
|---|---|---|
| 'KIF11' | 0.07 | 0.76 |
| 'KIF13A' | −0.29 | 0.17 |
| 'KIF13B' | −0.21 | 0.54 |
| 'KIF14' | −0.29 | 0.31 |
| 'KIF15' | 0.12 | 0.72 |
| 'KIF16B' | 0.19 | 0.47 |
| 'KIF17' | −0.06 | 0.61 |
| 'KIF18A' | 0.35 | 0.15 |
| 'KIF18B' | −0.04 | 0.88 |
| 'KIF1A' | 0.00 | 0.98 |
| 'KIF1B' | 0.37 | 0.18 |
| 'KIF1C' | −0.40 | 0.14 |
| 'KIF20A' | 0.49 | 0.09 |
| 'KIF21B' | −0.40 | 0.14 |
| 'KIF22' | −0.24 | 0.60 |
| 'KIF23' | 0.11 | 0.50 |
| 'KIF24' | −0.12 | 0.40 |
| 'KIF25' | −0.26 | 0.21 |
| 'KIF26B' | −0.05 | 0.76 |
| 'KIF2A' | −0.89 | 0.05 |
| 'KIF2C' | −0.08 | 0.81 |
| 'KIF3A' | −0.04 | 0.94 |
| 'KIF3B' | −0.63 | 0.12 |
| 'KIF3C' | −0.26 | 0.40 |
| 'KIF4A' | 0.58 | 0.09 |
| 'KIF5A' | −0.72 | 0.01 |
| 'KIF5B' | 0.47 | 0.27 |
| 'KIF5C' | −0.32 | 0.15 |
| 'KIFAP3' | −0.03 | 0.88 |
| 'KIFC1' | 0.03 | 0.88 |
| 'KIFC3' | −0.73 | 0.01 |
| 'MPHOSPH1' | −0.18 | 0.35 |
*
A positive result indicates a positive correlation with taxane response and a negative result a positive correlation with taxane resistance. Genes selected from penalized logistic regression are highlighted in bold.