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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: J Immunol. 2014 Apr 23;192(11):5130–5139. doi: 10.4049/jimmunol.1301677

Figure 8. IgE-mediated phosphorylation of IKK and SNAP23 is reduced in calpain-1 null mast cells.

Figure 8

Wild-type (+/+) and calpain-1 null (−/−) BMMCs were sensitized with anti-TNP IgE and stimulated with TNP-BSA for various times. Total cell lysates were analyzed by Western blotting for phosphorylated and total proteins of IKK and SNAP23 (Ser120). Phosphorylation of IKK and SNAP23 were impaired in calpain-1 null BMMCs. A representative photomicrograph is shown from three different cultures of BMMCs.