Figure 3. Six3 demarcates the PVN and SCN in Arx transgenic mice.
Representative coronal sections at the level of the optic chiasm and probed with Six3, are shown for wild type (left panels), Arx(GCG)7/Y (middle panels) and Arx−/Y (right panels) mice. For reference, the left periventricular nucleus (PVN) and suprachiasmatic nucleus (SCN) are enclosed by dotted lines in the wild type image. These nuclei are also normally expressing Six3 in the Arx transgenic animals. Scale bar = 200 µm.